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PDF Massive isotretinoin intoxication

We report a case of acute intoxication due to a massive overdose of isotretinoin A 29-year-old male patient ingested 900 mg of iso- tretinoin corresponding 

PDF Case report isotretinoin intoxication in attempted suicide: a case report

ABSTRACT We report a case of acute intoxication due to a massive overdose of isotretinoin A 17 year-old male patient

En cas de surdosage aigu par ACCUTANE, on devrait procéder à une évacuation gastrique au cours des premières heures suivant l'ingestion du médicament. Le surdosage aigu a été associé aux signes et symptômes suivants : céphalées, vomissements, rougeur faciale, chéilite, douleur abdominale, étourdissements et ataxie. Bien que sa toxicité aiguë soit faible, des signes d'hypervitaminose A pourraient survenir en cas de surdosage accidentel. Les symptômes d'hypervitaminose A comportent des céphalées intenses, des nausées ou vomissements, une somnolence, une irritabilité et un prurit.
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