cog msa 2016-2020


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PDF Convention d’objectifs et de gestion

2016-2020 L’expertise que développe la MSA sur de nombreux domaines et sa proximité de terrain permettent d’en faire un acteur reconnu sur les territoires Sur ce troisième axe la MSA confortera ses actions visant à accompagner les retraités dans leur avancée en âge sur leurs territoires de vie à améliorer les conditions de vie des

  • Quels sont les indicateurs de résultat de la COG MSA ?

    Indicateur de résultat 35% 40% 45% 50% 71 Annexes Annexe 1 : Règles budgétaires de la COG MSA pour la période 2016-2020 ........................................................................ Annexe 2 : FNGA Fond national de gestion administrative Annexe 3 : FNASS Fond national d’action sanitaire et sociale Annexe 4 : FNPEISA

  • Quels sont les objectifs de la MSA ?

    L’objectif est notamment de répondre pleinement au cadre réglementaire relatif au contrôle interne dans les organismes de sécurité sociale et de mettre en œuvre une politique coordonnée de lutte contre la fraude sociale et le travail illégal. Ces objectifs sont poursuivis dans le cadre d’une démarche d’amélioration continue. ENGAGEMENTS DE LA MSA

  • Comment étudier et porter les propositions de mutualisation de la MSA ?

    L’État s’engage à étudier et, le cas échéant, porter les propositions de mutualisation de la MSA en organisant les échanges avec les autres acteurs de la sphère sociale pour la mise en œuvre de mutualisations. 53

  • Comment la MSA a-t-elle contribué à la modernisation de la sphère sociale ?

    Enfin, les ministres ont encouragé la MSA, avec le concours de l’État, à se mobiliser dans le déploiement de nouvelles missions, au service de la modernisation de l’ensemble de la sphère sociale.

Introduction

Multiple system atrophy (MSA) is a sporadic neurodegenerative disease characterized by autonomic failure associated with a combination of cerebellar and/or parkinsonian signs. It is subclassified into a cerebellar (MSA-C) or parkinsonian (MSA-P) variant, depending on the predominant clinical phenotype (1). According to the diagnostic criteria for M

Materials and Methods

Patient Selection We retrospectively selected patients with a final clinical diagnosis of MSA referred to the movement disorders and autonomic disorders centers of our department, between 1991 and 2017, who were evaluated at least once a year during the disease course and who underwent at least one comprehensive neuropsychological evaluation. Among this group, we also analyzed the data of patients who underwent two neuropsychological evaluations (baseline evaluation = T0 and second evaluation = T1). Three neur

Statistical Analysis

The normality of the distribution of the continuous parameters was assessed using the skewness–kurtosis test. Continuous variables were compared using Student's test or Mann Whitney U-test. Categorical variables were described by their absolute and/or relative frequencies and compared using the chi square test. Because of the retrospective nature o

Results

Clinical, Neuropsychological, and Behavioral Baseline Evaluation A total of 145 patients with MSA were analyzed. Sixty patients (36 males, mean age at disease onset 57.6 ± 9.3, education 10.3 ± 4.7 years) underwent at least one neuropsychological evaluation and were included in the present study. Ten of these patients were enrolled in a previous prospective study by our team (12). Disease duration at neuropsychological evaluation was 5 ± 1 years. These patients did not differ in sex, age at onset, disease duration, or severity from those who did not underg

Discussion

Our study describes the cognitive profile and its evolution in a large cohort of patients with MSA, as assessed through a comprehensive neuropsychological battery and observed at the long disease duration and for the long follow-up period. We reported the frequency and profile of CI according to the clinical criteria for dementia and CI in our coho

Conclusions

In conclusion, our findings indicate that the cognitive profile of patients with MSA can be characterized by normal cognitive functioning even in the sixth year of the disease or by a selective and stable impairment of attention and executive functions that could be related to fronto-striatal-cerebellar dysfunction. This finding supports the idea t

Ethics Statement

The studies involving human participants were reviewed and approved by AUSL Committee, number of approval 17093. The patients/participants provided their written informed consent to participate in this study. frontiersin.org

Author Contributions

LS: conceptualization, formal analysis, data maturation, writing original draft, review, and editing. GC-B and IC: conceptualization, formal analysis, writing original draft, review, and editing. GG and MS: conceptualization, review, and editing. FP: conceptualization. RP and FO: conceptualization and data curation. PC: supervision, funding acquisi

Conflict of Interest

FP received honoraria for speaking engagements or consulting activities from Sanofi, Bial, Fidia, and Vanda Pharmaceutical. PC received honoraria for speaking engagements or consulting activities from Allergan Italia, AbbVie srl, Chiesi Farmaceutici, Eli Lilly, Novartis, Teva, UCB Pharma S.p.A, and Zambon. The remaining authors declare that the res

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